A 20 year old female with irregular cycles since 4 years ,pedal edema and abdominal distention since 2months

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Case presentation: A 20 year old female came  with chief complaints of irregular cycles since 4 years ,pedal edema and abdominal distention since 2 months.

HOPI : Pt was apparently asymptomatic 8years back then she developed regular menses for 1 month for year ,there after since 4 years back gradually developed irregular menses once for 6-7months and on consulting Doctor he prescribed medication (unknown),1cycled menses occurred and these irregularity continuing with out medication (LMP - 14/10/20),then 2 months back urine output gradually decreased and progressed.

Then edema developed which first occurred over abdomen and pt experienced Sob ,developed oliguria 2-3times/day approximately 50-60ml /day and edema progressed to both upper and lower limb and all over face over 10 days then went to mamatha hospital for further treatment.There on evaluation ,she developed microcytic hypochromic with few macrocytes and few target cells 

There is hyperpigmentation since 4 years

No H/o alopecia 

Past history:No similar complaints in past

No H/o fever ,cold,cough .

No H/o chest pain,palpitafions ,sweating ,syncopal attacks .

No H/o burning micturation,malena,diarrhoea,pale stools,constipation.

No H/o any surgeries ,blood transfusions

No H/o intake of iron tablets.

Sob on ingestion of food,not associated with pain

FAMILY HISTORY :No H/O similar complaints inthe family

PERSONAL HISTORY:

 He was on mixed diet, appetite normal, bowel habits normal ,no addictions

Menstrual history :

Attained menarche at the age of 12

Cycle :5/30, oligomenorrhea,no clots

LMP : 14/01/2020.



GENERAL EXAMINATION: pt is conscious, coherent, cooperative and oriented to time, place and person 

no pallor ,icterus,cyanosis,clubbing, lymphadenopathy

There is edema of both limbs which is pitting type

Acanthosis nigricans present














VITALS:


Temperature-99.8°f on presentation 


BP:120/80mmhg


PULSE:79pm


RR:19cpm


Spo2:98%


GRBS:103mg/dl


PER ABDOMEN:

INSPECTION : Abdomen bilaterally symmetrical.

Mild distention of abdomen,no flank fullness.

All quadrants moving equally with respiration.

Umbilicus is central and inverted.

No scars,sinuses,striae,pigmentation,echymosis,dilated veins and visible pulsations.

PALPATION: on palpation abdomen is soft and non tender 

No Guarding and rigidity. 

Spleen is palpable


PERCUSSION : No fluid thrill.no shifting dullness

AUSCULTATION : Bowel sounds  present.

CVS:s1 s2 heard


RS: BAE clear, normal vesicular breath sounds heard,no added sounds


CNS: 

MMSE:

MMSE:

1)Orientation: year,month,date,season,town,ward : NAT

Time,country,district,hospital: AT

Orientation total score (4/10)

2)Registration:registration for 3 objects: 3/3

3)Attention and calculation:0/5

4)recall after 5minutes:2/3

5)language for a)2objects : 2/2

b) 3stage command 3/3

c) return command 0/1

d) right sentence 0/1

e)repeat 1/1

6) Copying 1/1

Total score of MMSE = 15/30

Lobar function tests :                      

 1) Executive functions                 

A) History giving and insight of the problems - ++.

B) forward and backward digit span - NATD

C) as many words in a minute with any letter - NATD

D) naming any animal, vegetables, fruits in one minute : 2-3

E) motor Luria test : negative 

F) lobar integration  test : negative 

G)  Luria graphic test : NATD

H)  Set shifting A and B : NATD

2) Orbital and basal areas  of frontal lobe 

A)  dressing sense : good 

B) Go and no go test : good 

C)  stoop test : able to tell red colour and not for other colours 

3) Parietal lobe :

A) Ideational appraxia : good

B)  Right and left orientation : present 

C) finger agnosia : 

    a) non verbal finger recognition : +

    b)  identification  of named finger of the examiner : was confusing 

D)  visuospatial function : NATD

E)  cotical sensations : 

Asteregnosis present and graphasthesia was able to tell the direction  but not the letters 

F)  calculations  : NATD

4) Temporal lobe : memory and language : Good

5) Occipital lobe : 

a)  prosopagnosia : she is able to recognize familiar  faces 

b)  visual memory : didn't perform. 

Clock drawing test : NATD

NATD :Not able to do.

INVESTIGATIONS::

Thyroid profile:


     

USG



Gravendex test 

RFT 


LFT 

FBS

Day 1 :10th oct
No fresh complaints

O/E : pt is c/c/c

Vitals :pt is afebrile 
 Bp : 120 /80mmhg
PR : 84bpm
RR : 20c/m
Spo2 : 98%on room air 
Per abdomen : soft ,non tender
Cvs : s1s2 heard 
Rs : bilateral air entry present 
Cns : normal 
INVESTIGATIONS :
CUE
Hemogram




Treatment : 2egg whites / day
Tab MVT PO /OD

Day 2 :oct 11th
No fresh complaints

O/E : pt is c/c/c

Vitals :pt is afebrile 
 Bp : 110/60mmhg
PR : 72bpm
RR : 20c/m
Spo2 : 98%on room air 
Per abdomen : distended soft ,non tender
Cvs : s1s2 heard 
Rs : bilateral air entry present 
Cns : normal 
INVESTIGATIONS :

Serum ferritin

PLBS





ECG

Cxr





Treatment : 2egg whites / day
Tab MVT PO /OD

Day 3 : oct 12th



No fresh complaints

O/E : pt is c/c/c

Vitals :pt is afebrile 
 Bp : 120/80mmhg
PR : 76bpm
RR : 20c/m
Spo2 : 98%on room air 
Per abdomen : distended soft ,non tender
Cvs : s1s2 heard 
Rs : bilateral air entry present 
Cns : normal 
INVESTIGATIONS :


2D echo 







Review USG 




Treatment : 2egg whites / day
Tab MVT PO /OD

Day 4 :sep 13th

No fresh complaints

O/E : pt is c/c/c

Vitals :pt is afebrile 
 Bp : 110/80mmhg
PR : 72bpm
RR : 18c/m
Spo2 : 98%on room air 
Per abdomen : distended soft ,non tender
Cvs : s1s2 heard 
Rs : bilateral air entry present 
Cns : normal 
INVESTIGATIONS :

PT


APTT

ESR

Hemogram

HIV


HBsAg

Hcv






Treatment : 2egg whites / day
Tab MVT PO /OD



Diagnosis :Chronic liver disease and secondary amenorrhea (PCOS)under evaluation.



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